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Propofol is the most widely used intravenous anesthetic in modern medicine for good reason. It works primarily as a positive allosteric modulator of GABA-A receptors, opening chloride channels to produce rapid unconsciousness within 30 to 45 seconds. Because it is highly lipid soluble, it is formulated in an oil-in-water emulsion containing soybean oil and egg lecithin, giving it that characteristic white milk appearance. Reduces blood pressure, blunts airway reflexes, and wears off clean within
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