A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...
Researchers have identified serine threonine kinase 10 as a key regulator of platelet function, haemostasis and ...
Immunotherapy-based combinations have rapidly become the dominant first-line treatment for advanced hepatocellular carcinoma ...
Using high-speed atomic force microscopy (HS-AFM), the Kanazawa University team led by Mikihiro Shibata filmed the dynamic movements of CaMKII at the single-molecule level. The images revealed that a ...
Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...
Recent innovations in targeted protein degradation (TPD) extend beyond small-molecule PROTACs to encompass engineered peptides and recyclable ligand systems. Two complementary strategies─EGFR-directed ...
Collaboration partner, Gilead Sciences, to begin Phase 1 single ascending dose (SAD) and multiple ascending dose (MAD) study in healthy volunteers in Q2 2025 GS-6791/NX-0479 has potential clinical ...
Background: Hematopoietic progenitor kinase 1 (HPK1) is a member of the mitogen-activated protein kinase kinase kinase kinase (MAP4K) family. It has been reported that HPK1 negatively regulates the ...
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