Local sports talk radio station KNBR is moving its studios out of San Francisco and plans to operate out of Santa Clara at ...

Christian McCaffrey had 107 yards from scrimmage in his season debut. The 49ers are a different team when McCaffrey is on the ...

The season debut of Christian McCaffrey helped make the San Francisco 49ers offense look more like it did a year ago than it ...

The San Francisco 49ers are teetering on the brink of potential disaster on the injury front as they prepare for their Week ...

The San Francisco 49ers squeaked out a win against the Tampa Bay Buccaneers and will now host the Seattle Seahawks in an NFC ...

George Kittle earlier made his team-high seventh touchdown catch. San Francisco 49ers wide receiver Deebo Samuels, middle, ...

Cornerback Deommodore Lenoir, who has emerged as a cornerstone of the defense, agreed to a five-year extension.

NFL Week 11 odds, picks, predictions, TV and streaming information for the Sunday football game between the Seattle Seahawks ...

You can watch NFL games, including Fox broadcasts, with Hulu + Live TV, which includes 90 channels, unlimited DVR storage, ...

Former Oregon Ducks cornerback Deommodore Lenoir is now among the highest paid at his position in the National Football ...

The San Francisco 49ers play the Tampa Bay Buccaneers on Sunday. Here's everything you need to know about how to watch.

San Francisco 49ers cornerback Deommodore Lenoir has agreed to a five-year, $92 million extension to stay with the team ...