The San Francisco 49ers have been underdogs three times already this year and have lost twice. Their only win was over the ...

When the San Francisco 49ers square off with the Los Angeles Rams, it will be Sean McVay and Kyle Shanahan, Puka Nacua and ...

SANTA CLARA, Calif. — Quarterback Brock Purdy will miss his sixth straight start for the San Francisco 49ers with a toe ...

San Francisco 49ers defensive linemen Alfred Collins, Kalia Davis and Keion White failed to finish Thursday's practice. Each ...

Last week, residents were informed by the San Francisco Department of Health that a test taken in November 2024 at the former ...

Preview the NFL week 10 matchup between the Los Angeles Rams and 49ers, including betting odds, tips, trends, and game ...

NFL Week 10 odds, picks, predictions, TV channel, streaming information for the Sunday football game between Los Angeles Rams ...

Last week, the 49ers barely managed 10 total plays before halftime against the Houston Texans. On Sunday, however, the team ...

The San Francisco 49ers head to the New Jersey Meadowlands to face the New York Giants for NFL Week 9, and there are several ...

The 49ers have a few decisions to make on potential trade targets ahead of Tuesday's deadline. Who are the best fits for San ...

San Francisco 49ers running back Brian Robinson Jr. found the end zone for the first time this year on Sunday, and his ...

The San Francisco 49ers return home for Week 10 as they host the Los Angeles Rams at Levi's® Stadium. Fans can look forward ...