SCD gene therapy approaches using CRISPR, gene therapy, and base editing show different stem cell outcomes in a mouse study.

Thorough lentivirus characterization is essential for generating the highest quality gene therapy. Traditional methods only look at one piece of the puzzle, require purified samples, and can take days ...

VENLO, the Netherlands--(BUSINESS WIRE)--QIAGEN (NYSE: QGEN; Frankfurt Prime Standard: QIA) today announced the expansion of its cell and gene therapy (CGT) portfolio with an enhanced digital PCR ...

Viruses are small obligate intracellular parasites with either a RNA or DNA genome that are surrounded by a protective protein coat and transfer their genetic material to infected cells. Lentivirus ...

Jason Mast is a general assignment reporter at STAT focused on the science behind new medicines and the systems and people that decide whether that science ever reaches patients. You can reach Jason ...

Metachromatic leukodystrophy (MLD) is a rare genetic disorder caused by the deficiency of arylsulfatase A (ARSA) or its activator prosaposin (PSAP). This leads to the accumulation of sulfatides in the ...

Pharmaceutical Sciences Department, College of Pharmacy, Western University of Health Sciences, Pomona, CA, USA. The progression of HIV infection in a person living with HIV is dependent on the ...

Department of Chemical and Biomolecular Engineering, NC State University, 911 Partners Way, Raleigh, North Carolina 27606, United States NC-VVIRAL, NC State University, 1840 Entrepreneur Dr, Raleigh, ...

The LV Edge Packaging System has recently been launched to improve cost efficiency and reduce the supply chain risk of lentiviral production. The company claims the ready-to-transfer system minimizes ...

Viruses that belong to the genus Lentivirus of the family Retroviridae are exogenous, have specific morphology and contain a relatively complex retroviral genome. Vectors derived from lentiviruses can ...