Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Climate models have long spotlighted rising temperatures and extreme heat. Droughts, wildfires, and record highs dominate the narrative. But quietly, steadily, something else is disappearing: cold.

Epigenetics is the science of how your lifestyle, environment, and even emotions can alter your gene activity without ...

Long non-coding RNAs (lncRNAs) are RNA transcripts longer than 200 nucleotides that do not code for proteins. Once considered mere transcriptional noise, lncRNAs are now known to play vital roles in ...

Epigenetic changes, such as DNA methylation, chromatin remodeling, and histone modifications, regulate gene expression without altering the DNA sequence. This review systematically analyzed over 500 ...

Fruit ripening determines shelf life and consumer appeal, yet the molecular switches that control this process remain partially understood. This study identifies a key regulator—histone deacetylase ...

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a leading cause of cancer-related deaths worldwide. While environmental and genetic factors contribute to HCC, increasing ...

Department of Oncology Science, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States Glioblastoma (GBM), a highly aggressive and malignant form of primary adult brain cancer ...

Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...