Human immunodeficiency virus (HIV) infection is a viral infection that causes acquired immunodeficiency syndrome (AIDS) by gradually destroying certain leukocytes. When HIV enters the human body, it ...

Purpose: The mechanism of action, pharmacology, pharmacokinetics, clinical efficacy, drug interactions, adverse effects, dosage and administration, cost, and role in therapy of maraviroc are reviewed.

December 20, 2010 — Replacing host stem cells with donor-derived cells homozygous for the CCR5 gene variant Δ32 (CCR5Δ32/Δ32) resulted in the HIV viral reservoir being reduced over time, strongly ...

RICHMOND, Calif., Feb. 3 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that its collaborators at the University of Pennsylvania ...

The CCR5 co-receptor is necessary for cellular entry by R5 tropic viral strains involved in primary HIV infection, but is dispensable for normal human physiology. Owing to its crucial role in HIV-1 ...

We have recently reported that the mean number of CCR5 coreceptors at the surface of CD4+ T cells (CCR5 density) correlates with viral load and disease progression in HIV-1-infected persons. Here, we ...

CCR5 Antagonists Market in HIV & Rare Inflammatory Conditions to Reach $300 Million by 2025, Driven by Expanding Clinical Pipeline and Indication Diversification The global CCR5 antagonists market ...

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With Gift Aid, your generous donation of £10 would be worth £12.50 at no extra cost to you. Yes, I want to Gift Aid any donations made to NAM now, in the future and in the past four years I am a UK ...

Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that its collaborators at the University of Pennsylvania have opened a Phase 1 clinical trial to evaluate SB-728-T for the treatment of ...