The 49ers have had a roller-coaster of a season so far. There have been numerous injuries to key players, including Brock ...

For the sixth consecutive game, the San Francisco 49ers will not have Ricky Pearsall available. Pearsall is still working his ...

Defensive end Clelin Ferrell had a sack to help the 49ers beat the Giants last Sunday and he'll get another chance to rush ...

On Sunday, Nov. 9 (kicking off at 4:25 p.m. ET), the Los Angeles Rams (6-2) play the San Francisco 49ers (6-3) at Levi's ...

The LA Rams and San Francisco 49ers will square off for the second time in six weeks as they renew their rivalry at Levi's ...

The rivalry takes on added meaning with the Rams, who have won three in a row since losing to the Niners in Week 5, needing ...

Asante Samuel Jr. to boost secondary after injuries. Analyst explains urgency, fit, and postseason Super Bowl impact.

Brady is referencing the 49ers drafting quarterback Giovanni Carmazzi over him in the 2000 NFL Draft. He was selected in the ...

Will 49ers defensive end Bryce Huff return to game action this Sunday for the team's showdown against the Rams?

San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams ...

USA TODAY NFL columnist Jarrett Bell's midseason plaudits trumpet 49ers coach, Philly's QB, Browns' Myles Garrett.

The Los Angeles Rams face a significant matchup in Santa Clara against the San Francisco 49ers in an effort to avenge their ...