The human genome encodes instructions for which genes are expressed in what cell type, along with other molecules that control how much and when these genes are expressed. Variation in the regulation ...
As the body ages, organ function progressively declines and the risk for a wide range of diseases, including cardiovascular disease, cancer, and neurodegenerative diseases increases. Understanding how ...
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Alzheimer's erodes brain cells' control of gene expression, undermining function and cognition
Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...
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Gene expression study reveals human brain cell types becoming more specialized, not just more numerous
Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...
Kouichi Tamura, Yuqing E. Chen, Masatsugu Horiuchi, Qin Chen, Laurent Daviet, Zhiyong Yang, Marco Lopez-Ilasaca, Hui Mu, Richard E. Pratt, Victor J. Dzau Proceedings of the National Academy of ...
A chromatin is comprised of 147 base pairs of DNA wrapped around a protein core referred to as a histone. The histone is comprised of two units each of H2A, H2B, H3, and H4, making an octamer. The ...
This is a preview. Log in through your library . Abstract Phase II of germination represents a key developmental stage of plant growth during which imbibed seeds either enter stage III of germination, ...
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Scientists revive diabetic beta cells, revealing a new path to restore insulin function
Researchers demonstrated that pancreatic β cells from type 2 diabetes donors can partially regain glucose responsiveness when ...
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