Prophecy centers entirely around the origins of the Bene Gesserit, known only as "the Sisterhood" in the show. However, there's a very simple reason for that. "The Sisterhood at its inception is not called the Bene Gesserit,

The series chronicles the early evolution of the Bene Gesserit order into a superpowered mystical sisterhood with great political power.

Dune: Prophecy premiered on HBO and is now available for streaming on Max, and fans want to know when it is set in the Dune franchise’s timeline. The plot revolves around siblings Valya and Tula Harkonnen as they emerge as pivotal figures in humanity’s history and the Bene Gesserit,

Dune: Prophecy is HBO’s latest installment in the Dune franchise and the setting might be a little complicated, but still explores the feud between House Harkonnen and House Atreides. Dune: Prophecy serves as a prequel to Denis Villeneuve’s Dune films.