A defining characteristic of cancer cells is their immortality. Usually, normal cells are limited in the number of times they can divide before they stop growing. Cancer cells, however, can overcome ...
A new study led by researchers at the University of Pittsburgh (Pitt) and UPMC Hillman Cancer Center has shown that an enzyme called PARP1 is involved in the repair of telomeres, the lengths of DNA ...
A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of ...
A defining characteristic of cancer cells is their immortality. Usually, normal cells are limited in the number of times they can divide before they stop growing. Cancer cells, however, can overcome ...
Imagine your DNA as a set of shoelaces. Telomeres are like the plastic tips at the ends of those shoelaces, preventing them from fraying and unraveling. Structurally, telomeres are repetitive ...
Five-year NIH-funded study will examine how early-life factors such as growth patterns and exposure to air pollution affect ...
Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...
In the quest to unlock the secrets of aging and longevity, telomeres have emerged as key players. These protective caps at the ends of our chromosomes play a critical role in cellular aging. With each ...
In absence of TARG1, ADP-ribose accumulated at telomeres, leading to disruption of telomere replication and premature telomere shortening. To show that these telomere defects were due to modification ...
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