In the 1950s and 1960s, according to a theory known as the British hypothesis, repeated airway infection and hypersecretion of mucus were thought to be the causes of chronic obstructive pulmonary ...

Two main biologic mechanisms can lead to chronic obstructive pulmonary disease (COPD) in adulthood: abnormal lung development and an increased rate of lung-function decline with age. These mechanisms ...

The role that eosinophilic chronic obstructive pulmonary disease (COPD) plays in the pathogenesis of COPD is not well understood, given the lack of evidence about the subject. A review focusing on the ...

The current pathophysiology of COPD encompasses three main characteristics: emphysema, chronic bronchitis and small airway disease. Macrophages and neutrophils are implicated in this process; thus ...

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a new study that analyzed human genome information. Autoimmunity plays a role in the ...

Chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by sustained neutrophilic airway inflammation, is caused by chronic exposure to noxious stimuli, e.g., cigarette ...

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a study led by Georgia State University and Vanderbilt University Medical Center that ...