In a recent study published in the Cell Reports journal, researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition. Studies have shown that exposing esophageal cells to ...

The protein p53, best known as the "guardian of the genome" for its role in preventing cancer, can affect blood vessels in ...

In the 1970s, scientists knew that some viruses and chemicals caused cancer, but they didn’t know how. Arnold Levine, a biologist currently at the Institute for Advanced Study researched DNA viruses ...

The tumor-suppressing protein p53 has long been considered a valuable target—if only drug hunters could figure out how to hit it. Many research efforts aiming to leverage the capabilities of this ...

Researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the ...

New research has found the protein p53 plays a key role in epithelial migration and tissue repair. The findings could improve our understanding of the processes used by cells to repair tissues, and be ...

The process of cell growth and division is controlled by genes. When this normal process goes awry, cells can grow out of control, forming cancer and producing new proteins that continue to feed the ...

Epidermal growth factor receptor (EGFR) immunohistochemistry: Comparison of antibodies (Abs) and cut points to predict benefit from gefitinib in a phase III placebo-controlled study in advanced ...

Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the cell.

image: Nien-Pei Tsai, a researcher at the Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign, led a team of researchers to establish the protein p53 ...