The Chiefs enter Week 11 as the NFL's only undefeated team. Kansas City has won nine consecutive games to open the season, but the Chiefs are just 5-4 against the spread. The Chiefs are 2.5-point underdogs in the Week 11 NFL odds after the line opened at Kansas City -1.

Here's everything you need to know for Week 11 NFL games. Which teams will win, who are the X factors, and which storylines matter most?

The Seattle Seahawks (4-5) are 6.5-point underdogs in a road NFC West matchup with the San Francisco 49ers (5-4) on Sunday, November 17, 2024 at Levi’s Stadium.NFL odds courtesy of BetMGM

SportsLine's advanced model has locked in its Week 11 NFL betting picks and football predictions from 10,000 simulations

Sportsbooks give the San Francisco 49ers (5-4) the edge when they host the Seattle Seahawks (4-5) on Sunday, November 17, 2024 in a matchup between NFC West foes at Levi’s Stadium. San

The Indianapolis Colts (4-6) are 4-point underdogs as they aim to stop their three-game losing streak in a matchup with the New York Jets (3-7) on Sunday, November 17, 2024 at MetLife Stadium.NFL

The NFL playoff picture is starting to come into focus heading into the Week 11 of the 2024 season. Thanks to a blocked field goal on the final play of the game, the Kansas City Chiefs (9-0) kept their perfect record in tact with a 16-14 win over the Denver Broncos in Week 10.

Chris Simms and Mike Florio go head-to-head on their best bets for Week 11 of the 2024 NFL season, explaining why they believe the Green Bay Packers and San Francisco 49ers should be favored more heavily.