Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme, as a third structural component of the ...
针对肺动脉高压(PH)中糖酵解重编程的分子机制不明问题，东南大学团队开展LONP1-MPC1调控通路研究。发现LONP1通过降解线粒体丙酮酸载体1(MPC1)促进肺动脉平滑肌细胞(PASMCs)糖酵解重编程和异常增殖 ...
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