When inflammation in the body goes unchecked, it can cause fibrosis, or tissue scarring that may lead to organ dysfunction or ...

The gut bacteria B. adolescentis eased lung scarring in a pulmonary fibrosis mouse model, showing potential as a preventive ...

Fat—adipose tissue—is more complicated than might be thought. Once considered just a bag of calories, scientists now know that fat doesn’t just squirrel away energy, it also sends and receives ...

Helmholtz Munich researchers revealed a conserved differentiation process with clinical implications for injury repair, identifying a multipotent fibroblast progenitor in the fascia— the deepest ...

Pinpointing the precise culprits behind harmful biological processes—such as excessive scarring (fibrosis) in organs like the kidneys and lungs—has long remained challenging even though this affects ...

LA JOLLA (December 6, 2023)—Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick ...

Healing from any injury involves a delicate balance between scarring and inflammation — two processes that can wreak havoc as well as make repairs. When the injury is to the brain, the balance is that ...

Researchers at WashU Medicine have reduced scar formation and improved heart function in mouse models of heart failure using a monoclonal antibody treatment. Untreated mice develop major scarring ...

Creeping fat — the abnormal expansion of mesenteric adipose tissue around the intestines — is an active driver of intestinal scarring in Crohn’s disease (CD), highlighting a potential new therapeutic ...