Release of charged neurotransmitter molecules through a narrow fusion pore requires charge compensation by other ions. It has been proposed that this may occur by ion flow from the cytosol through ...

Although elevated urinary catecholamine levels have been reported in 90–95% of patients with neuroblastoma, more recent studies of pediatric Horner syndrome caused by an underling neuroblastoma have ...

PROMINENT among the symptoms of familial dysautonomia are the manifestations of autonomic dysfunction. 1 A disturbance in catecholamine metabolism has been documented by the demonstration of high ...

Injection of frogs with β -adrenergic catecholamines for 1-24 hr produces marked subsensitivity of the erythrocyte membrane adenylate cyclase [ATP pyrophosphate-lyase (cyclizing); EC 4.6.1.1] to in ...

Association Between Human Epidermal Growth Factor Receptor 2-Low Status and Time to Development of Brain Metastases Among Patients With Breast Cancer: A Retrospective Cohort Study These results ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 70, No. 8 (1973), pp. 2411-2414 (4 pages) Depletion of neural norepinephrine by reserpine treatment or by ...

Pheochromocytomas are neural crest-derived tumors that produce catecholamines, such as epinephrine and norepinephrine, and arise mainly from the adrenal gland. Closely affiliated tumors of ...

Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is a rare genetic ventricular tachycardia which can result in sudden cardiac death and/or syncope in young individuals with structurally ...

Renalase is a relatively recently discovered kidney protein connected to chronic kidney disease and blood pressure disorders. It functions by metabolizing catecholamines and similar substances, such ...

These cases serve as exemplars of the types of cardiac dysfunction that frequently accompany aneurysmal SAH (at our institution, we identified a 33% incidence of cardiac dysfunction following SAH, ...

The abnormality in catecholamine metabolism has now been further explored by measurement of the catecholamine content of the adrenal glands and heart muscle of children dying with dysautonomia. The ...