The calcium-sensing receptor (CaSR) is a class C G-protein-coupled receptor that serves as a central regulator of extracellular calcium homeostasis by modulating parathyroid hormone (PTH) secretion ...

The calcium-sensing receptor is critical for maintaining healthy calcium levels, but CaSR is also well-known for its side hustles. The receptor is increasingly recognized for its ability to detect ...

Calcium-sensing receptors (CaSRs), widely distributed in tissues and organs such as parathyroid glands, intestines, bones and kidneys, sense the concentration of calcium ions in the blood and maintain ...

Researchers have identified a previously unknown mechanism by which the kidney precisely controls calcium excretion. The claudin-14 protein plays a key role in this process: It displaces the ...