ATP hydrolysis releases the energy required for myosin to do its job. AF: actin filament; MF myosin filament. Modified from Goody (2003).
The swinging cross bridge theory for muscle contraction envisages that the myosin cross bridge binds to the actin filament in an initial conformation and then undergoes a swinging motion that 'rows' ...
Hypertrophic cardiomyopathy (HCM) is the most common inherited form of heart disease, associated with over 1,000 mutations, many in β-cardiac myosin (MYH7). Molecular studies of myosin with different ...
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