Of the 16 players listed, 14 have injuries, one has an illness (wide receiver Marvin Harrison Jr.) and one has a personal issue (defensive lineman Bilal Nichols). Even tackle Kelvin Beachum, who always has a rest day on Wednesday, now also has a groin injury.

The 2024 version of the Arizona Cardinals ended the season as one of the most injured teams in the NFL, and this year is shaping up to be even worse.

The Cardinals are not worried about rookie defensive linemen Walter Nolen III's leg injury suffered in Week 10 loss to Seahawks

The Arizona Cardinals have not yet released their first injury report of the week, but head coach Jonathan Gannon already ruled out some players for Week 11 as they prepare to play the San Francisco 49ers Sunday at State Farm Stadium. The biggest news was that receiver Marvin Harrison Jr. will have an appendectomy and will miss at least one game.

The Arizona Cardinals’ 44-22 loss to the Seattle Seahawks on Sunday is a snapshot of a team still looking for structure under head coach Jonathon Gannon.