Brady is referencing the 49ers drafting quarterback Giovanni Carmazzi over him in the 2000 NFL Draft. He was selected in the third round, at pick 65, by the 49ers. He played just two seasons in San Francisco before leaving the NFL less than two years after being drafted.

The 49ers played possum Tuesday rather than buy into the New York Jets’ Tuesday fire sale or pony up for any other household names amid their injury woes.

The San Francisco 49ers didn't make a trade at the NFL trade deadline, but head coach Kyle Shanahan said it wasn't for a lack of effort.

Asante Samuel Jr. to boost secondary after injuries. Analyst explains urgency, fit, and postseason Super Bowl impact.

The San Francisco 49ers on Saturday elevated rookie DT Sebastian Valdez and D-lineman Clelin Ferrell to face the Los Angeles Rams on Sunday.

San Francisco 49ers head coach Kyle Shanahan announced the team's starting quarterback for Week 10's matchup against the Rams.

George Kittle has just 75 yards in the three games that he has played since returning from an injury that sidelined him for five games. It has fantasy football