Nine people remain missing after a UPS plane departing Louisville Muhammad Ali International Airport in Kentucky on Tuesday crashed, killing at least 12 people.

The NTSB confirmed a UPS cargo plane's left engine separated during takeoff before a fatal Louisville airport crash that killed 12 people and injured 11 others Tuesday.

The power had just gone off and the ground was shaking at Grade A Auto Parts when the owner received a panicked video call from his chief financial officer. On his screen, CEO Sean Garber watched a “huge fireball” engulf the Louisville,

The plane crashed and burst into flames on Tuesday in Louisville, killing at least 12 people and injuring nearly 20 others. The disaster also shut down the largest UPS package distribution hub.

UPS cargo plane crashes near Louisville airport; multiple victims confirmed as crews continue search in damaged industrial sites.

The Federal Aviation Administration (FAA) and the National Transportation Safety Board (NTSB) will lead the investigation into the incident.

At least 12 people were killed and several others injured after a UPS plane crashed shortly after taking off from the Louisville International Airport on Tuesday.